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Chinese Journal of Experimental and Clinical Virology ; (6): 219-221, 2008.
Article in Chinese | WPRIM | ID: wpr-254098

ABSTRACT

<p><b>OBJECTIVE</b>To approach the effect of HAART to serum soluble interleukin-2 receptors in AIDS patients.</p><p><b>METHODS</b>90 cases of AIDS patients were chosen for detection of their slL-2R levels by enzyme-linked immunosorbent assay (ELISA), peripheral blood CD4 T cell counts by flow cytometry and viral load by Branch DNA amplification.</p><p><b>RESULTS</b>The slL-2R levels were (3154 +/- 905) m9icrog/ml before HAART and (2216 +/- 884) pg/ml after( P < 0.001), After HAART, the sIL-2R levels were(2846 +/- 963) microg/ml in ineffective HAART group and (1879 +/- 875) pg/ml in effective HAART group (P < 0.001).</p><p><b>CONCLUSION</b>The serum sIL-2R levels of AIDS patients were lowered by effective HAART, and it could judge the efficacy of HAART in same extent.</p>


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Acquired Immunodeficiency Syndrome , Drug Therapy , Allergy and Immunology , Antiretroviral Therapy, Highly Active , CD4 Lymphocyte Count , Receptors, Interleukin-2 , Blood , Viral Load
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